In vitro oxidation promoted by sarafloxacin antibiotic residues on myosin and chicken meat proteins

نویسندگان

چکیده

Fluoroquinolones are widely employed to treat or prevent respiratory diseases in poultry, and their residues could be present even after slaughtering. Thus, this study aimed assess the oxidative effect of fluoroquinolones on myosin chicken meat proteins under vitro conditions, using proteomics peptidomics approaches. Myosin was initially exposed ciprofloxacin sarafloxacin, which showed an increase protein carbonylation over time, especially with sarafloxacin. Then, skipped sarafloxacin its gastrointestinal digestion, main were isolated subsequently identified by mass spectrometry tandem. The more susceptible oxidation myosin, β-enolase, CK-M-type, actin. After analysis, collagen peptides resulted as most prone damage. These findings confirm potential negative effects affect nutritional technological properties.

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ژورنال

عنوان ژورنال: Journal of Food Composition and Analysis

سال: 2022

ISSN: ['0889-1575', '1096-0481']

DOI: https://doi.org/10.1016/j.jfca.2022.104622